While the connection between schizophrenia and breast cancer is an important point of consideration for both clinicians and researchers, it is complex and difficult to fully describe. This systematic literature review of clinical studies found that results were widely discrepant, which may be understood in terms of various cohort qualities. Those studies with more than 100 incident cases of breast cancer and greater than 100,000 person years of follow up were more likely to report an increased or marginally increased incidence of breast cancer. The article discusses various factors that may result in discrepant study outcomes.
